- The title of the episode derives from the term two-lane blacktop, used to describe a paved street. There was a film called 2-Lane Blacktop made in 1971.
- During the street race, the music that plays is the 1972 rock classic Highway Star by Deep Purple.
- At the scrapyard, Sal melts down Speed Buggy (from the cartoon of the same name), and the Mach-5 from Speed Racer. The title character from that cartoon looks on, distressed.
- Leela goes shopping at the Thingy Wiggly supermarket, a parody of the Piggly Wiggly grocery chain. The creature pictured on the store's marquee is the Martian Leader from 1953's Invaders From Mars.
- The 2D inhabitants call themselves The Lords Of Flatbush, referencing a 1974 film with that title.